Revista: | Brazilian Journal of Pharmaceutical Sciences |
Base de datos: | PERIÓDICA |
Número de sistema: | 000451757 |
ISSN: | 1984-8250 |
Autors: | Bezerra, José Jailson Lima1 Nascimento, Ticiano Gomes do2 Kamiya, Regianne Umeko3 Prata, Ana Paula do Nascimento1 Medeiros, Patrícia Muniz de1 Silva, Sâmia Andrícia Souza da2 Melo, Nathaly Esperidião de3 |
Institucions: | 1Universidade Federal de Alagoas, Campus de Engenharias e Ciencias Agrarias, Rio Largo, Alagoas. Brasil 2Universidade Federal de Alagoas, Instituto de Ciencias Farmaceuticas, Maceio, Alagoas. Brasil 3Universidade Federal de Alagoas, Instituto de Ciencias Biologicas e da Saude, Maceio, Alagoas. Brasil |
Any: | 2022 |
Volum: | 58 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, aplicado |
Resumen en inglés | Several factors contribute to the resistance of some pathogenic microorganisms and this fact requires the search for new therapeutic alternatives. The genus Cyperus (family Cyperaceae) groups species that present chemical compounds of pharmacological interest, mainly with antimicrobial action. Thus, the present work was carried out to investigate the antimicrobial activities, antioxidants and the phytochemical profile of Cyperus articulatus L. and Cyperus iria L. Hydroalcoholic extracts (1:1, v:v) of the aerial and underground parts of these species were used to analyze the total phenol content and to evaluate the in vitro antioxidant activity against the DPPH (2,2-diphenyl-1-picrylhydrazyl). The ethyl acetate and chloroform phases resulting from liquid-liquid partitioning of C. articulatus and C. iria extracts were evaluated in antimicrobial assays and subject to high performance liquid chromatography (HPLC-DAD) analysis. The chromatograms obtained by HPLC-DAD allowed us to identify four compounds: chlorogenic acid, catechin, quercetin, and quercitrin. The hydroalcoholic extracts of C. articulatus and C. iria showed a weak antioxidant activity with IC50 of 395.57 and 321.33 μg/mL (aerial parts), and 1,114.01 and 436.82 μg/mL (underground parts), respectively. Regarding antimicrobial activity, the chloroform phase of C. iria showed the best result at the concentration of only 31.2 µg/mL against the pathogens Candida albicans and Staphylococcus aureus. The ethyl acetate phases of the aerial parts of C. articulatus and C. iria did not show antimicrobial activity |
Disciplines | Biología, Química |
Paraules clau: | Angiospermas, Fitoquímica, Extractos vegetales, Plantas medicinales, Actividad biológica, Cyperus articulatus, Cyperus iria, Cyperaceae |
Keyword: | Angiosperms, Phytochemistry, Plant extracts, Biological activity, Cyperus articulatus, Cyperus iria, Cyperaceae |
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