| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000450971 |
| ISSN: | 1984-8250 |
| Autors: | Wissam, Zam1 Samer, Housheh1 |
| Institucions: | 1Al-Andalus University for Medical University, Faculty of Pharmacy, Tartous. Siria |
| Any: | 2019 |
| Volum: | 55 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil |
| Disciplines | Química |
| Paraules clau: | Química farmacéutica, Aceites vegetales, Linaza, Encapsulación, Alginato de sodio, Linum usitatissimum, Gramineae |
| Keyword: | Medicinal chemistry, Plant oils, Flaxseed, Encapsulation, Sodium alginate, Linum usitatissimum, Gramineae |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
