Early life, current socioeconomic position and serum lipids in young adulthood of participants in a cohort study initiated in 1978/1979
Título del documento: Early life, current socioeconomic position and serum lipids in young adulthood of participants in a cohort study initiated in 1978/1979
Revista: Brazilian journal of medical and biological research
Base de datos: PERIÓDICA
Número de sistema: 000351881
ISSN: 0100-879X
Autors: 1
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3
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2
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2
Institucions: 1Universidade Federal do Maranhao, Departamento de Saude Publica, Sao Luis, Maranhao. Brasil
2Universidade Federal do Maranhao, Departamento de Medicina III, Sao Luis, Maranhao. Brasil
3Universidade de Sao Paulo, Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil
Any:
Període: Sep
Volum: 40
Número: 9
Paginació: 1267-1276
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés The association between socioeconomic position (SEP) and serum lipids has been little studied and the results have been controversial. A total of 2063 young adults born in 1978/79 were evaluated at 23-25 years of age in the fourth follow-up of a cohort study carried out in Ribeirão Preto, SP, Brazil, corresponding to 31.8% of the original sample. Total serum cholesterol (TC), triglycerides, high-density cholesterol (HDL cholesterol) and low-density cholesterol (LDL cholesterol) were analyzed according to SEP at birth and during young adulthood. SEP was classified into tertiles of family income and a cumulative score of socioeconomic disadvantage was created. TC was 11.85 mg/100 mL lower among men of lower SEP in childhood (P < 0.01) but no difference was found in women, whereas it was 8.46 lower among men (P < 0.01) and 8.21 lower among women of lower SEP in adulthood (P < 0.05). Individuals of lower SEP had lower LDL and HDL cholesterol, with small differences between sexes and between the two times in life. There was no association between SEP and triglyceride levels. After adjustment of income at one time point in relation to the other, some associations lost significance. The greater the socioeconomic disadvantage accumulated along life, the lower the levels of TC, LDL and HDL cholesterol (P < 0.05). The socioeconomic gradient of TC and LDL cholesterol was inverse, representing a lower cardiovascular risk for individuals of lower SEP, while the socioeconomic gradient of HDL cholesterol indicated a lower cardiovascular risk for individuals of higher SEP
Disciplines Medicina
Paraules clau: Pediatría,
Salud pública,
Estudios de cohorte,
Metabolismo,
Colesterol,
Triglicéridos,
Enfermedades cardiovasculares,
Nivel socioeconómico
Keyword: Medicine,
Pediatrics,
Public health,
Cohort studies,
Metabolism,
Cholesterol,
Triglycerides,
Cardiovascular diseases,
Socioeconomic level
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