Comparison of biomass estimation techniques for a Bacillus thuringiensis fed-batch culture



Título del documento: Comparison of biomass estimation techniques for a Bacillus thuringiensis fed-batch culture
Revista: Brazilian journal of chemical engineering
Base de datos: PERIÓDICA
Número de sistema: 000308762
ISSN: 0104-6632
Autors: 1
2
Institucions: 1University of Newcastle upon Tyne Merz Court, Department of Chemical and Process Engineering, Newcastle, Tyne. Reino Unido
2Universidade Federal do Rio de Janeiro, Centro de Tecnologia, Rio de Janeiro. Brasil
Any:
Període: Mar
Volum: 18
Número: 1
Paginació: 35-45
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés In this work, the ability of artificial neural nets was investigated for the on-line biomass prediction of the simulated growth of a strain of Bacillus thuringiensis in fed-batch mode. For this purpose, multilayered backpropagation nets with sigmoid nodes were trained. The patterns were composed of input data on current values of biomass concentration, limiting substrate concentration and dilution rate, and output data on prediction of biomass concentration for the following step. The dilution rate was disturbed by a PRBS input, and simulations were conducted using a phenomenological experimentally validated model. The nets were able to predict the biomass concentration for different feeding techniques, and they were also compared with the variable estimation technique using the extended Kalman filter
Disciplines Química
Paraules clau: Fermentaciones,
Cultivo por lotes,
Biomasa,
Filtro Kalman,
Redes neuronales,
Bacillus thuringiensis
Keyword: Chemistry,
Fermentation,
Fed-batch culture,
Biomass,
Kalman filter,
Neural networks,
Bacillus thuringiensis
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