| Revista: | Brazilian journal of chemical engineering |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000308895 |
| ISSN: | 0104-6632 |
| Autors: | Cremasco, M.A1 Guirardello, R Linda Wang, N.-H2 |
| Institucions: | 1Universidade Estadual de Campinas, Faculdade de Engenharia Quimica, Campinas, Sao Paulo. Brasil 2Purdue University, Department of Chemical Engineering, West Lafayette, Indiana. Estados Unidos de América |
| Any: | 2003 |
| Període: | Sep |
| Volum: | 20 |
| Número: | 3 |
| Paginació: | 327-334 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | Phenylalanine (Phe) and tyrosine (Tyr) are two of the twenty amino acids in proteins; they are classified as aromatic amino acids, because both have a benzene ring in their structures. These amino acids are important in the synthesis of several biologically active amines, such as beta-endorphin, a neurotransmitter. Amino acids can be separated by ion-exchange chromatography. In this case, it is important that fixed-bed adsorber design adequately predict the breakthrough curve. This work presents a mathematical model for both fluid and porous phases. In the solution proposed for this model the liquid-phase concentration inside the particles is solved analytically and is related to the liquid-phase concentration in the bed using Duhamel's theorem. The solution for liquid-phase concentration in the bed is then solved numerically instead of analytically. The basic mass transfer parameters are from the literature. The results from the model are compared with those obtained experimentally using Phe and Tyr diluted in aqueous solutions in a fixed bed of PVP (poly-4-vinylpyridine) resin |
| Disciplines | Química |
| Paraules clau: | Ingeniería química, Aminoacidos aromáticos, Adsorción, Columnas de lecho empacado |
| Keyword: | Chemistry, Chemical engineering, Aromatic amino acids, Adsorption, Fixed bed columns |
| Text complet: | Texto completo (Ver HTML) |
