TT virus in peripheral blood cells from patients with human papillomavirus (HPV): investigating association with cervical carcinoma
Título del documento: TT virus in peripheral blood cells from patients with human papillomavirus (HPV): investigating association with cervical carcinoma
Revista: Brazilian archives of biology and technology
Base de datos: PERIÓDICA
Número de sistema: 000374420
ISSN: 1516-8913
Autors: 1
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2
3
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Institucions: 1Universidade Estadual de Londrina, Centro de Ciencias Biologicas, Londrina, Parana. Brasil
2Hospital do Cancer de Londrina, Londrina, Parana. Brasil
3Universidade Estadual de Maringa, Laboratorio de Analises Clinicas, Maringa, Parana. Brasil
Any:
Període: Mar-Abr
Volum: 57
Número: 2
Paginació: 228-232
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés Torque Teno Virus (TTV) presence was investigated in peripheral blood of 117 brazilian women by nested polymerase chain reaction. TTV DNA was observed in 18.6% of healthy donors and in 24.32% Human Papillomavirus (HPV) patients. TTV presence was also investigated in the HPV positive group for comparison between the cervical cancer and noncancerous patients. TTV DNA prevalence was significantly higher among the HPV positive patients with cervical cancer (57.14%) than in HPV noncancerous patients (16.67%). Thus, the presence of TTV infection could be a risk factor for cancer development in the patients presenting HPV-TTV coinfection. Further studies are required to clarify the TTV influence in HPV pathogenesis
Disciplines Biología,
Medicina,
Química
Paraules clau: Virus,
Hematología,
Bioquímica,
Torque teno virus (TTV),
ADN TTV,
Virus del papiloma humano (VPH),
Cáncer cervical
Keyword: Biology,
Medicine,
Chemistry,
Virus,
Hematology,
Biochemistry,
Torque teno virus (TTV),
TTV DNA,
Human papillomavirus (HPV),
Cervical cancer
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