| Revista: | Belize journal of medicine |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000418967 |
| ISSN: | 2225-8116 |
| Autors: | Hirzel, Alicia1 Sriganeshan, Vathany1 |
| Institucions: | 1Mount Sinai Medical Center, Department of Pathology and Laboratory Medicine, Miami, Florida. Estados Unidos de América |
| Any: | 2013 |
| Període: | Jul |
| Volum: | 2 |
| Número: | 2 |
| Paginació: | 7-11 |
| País: | Belice |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Lymphoma and Pneumocystis jiroveci infection are well-described entities in Human immunodeficiency/Acquired immunodeficiency syndrome (HIV/AIDS) patients. They are both AIDS defining diseases according to the World Health Organization (WHO). Although they are known to occur frequently in this patient population, concurrent B cell lymphoma and Pneumocystis jiroveci pneumonia, has not been reported in the literature. We describe the case of an HIV/AIDS patient with no history of anti-retroviral therapy, previously diagnosed lymphoma or treatment with chemotherapy, who was diagnosed with HIV during a recent incarceration, during which he developed fever, shortness of breath and fatigue. Due to the complex nature of his clinical presentation, a pulmonary lobectomy was performed. Grossly there was an ill-defined, friable, necrotic mass. Microscopically, there was an exudate consistent with Pneumocystis jiroveci and atypical lymphoid cells scattered throughout the necrotic tissue. Immunohistochemical stains demonstrated positivity of these lymphoid cells with CD20, PAX5, BCL2 and MUM1 with a diagnosis of large B cell lymphoma, activated type. A case of concurrent Pneumocystis and B cell lymphoma developing in an HIV/AIDS patient with no history of chemotherapy has not been reported to our knowledge |
| Disciplines | Medicina |
| Paraules clau: | Neumología, Inmunología, Oncología, Pneumocystis jiroveci, Pneumonia, Large B-cell lymphoma, HIV, SIDA |
| Keyword: | Pneumology, Microbiology, Oncology, Pneumocystis jiroveci, Large B-cell lymphoma, HIV, AIDS |
| Text complet: | Texto completo (Ver PDF) |
