| Revista: | Archives of clinical psychiatry |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000413934 |
| Autors: | Campos-Carli, Salvina Maria de1 Vieira, Erica Leandro Marciano1 Rocha, Natalia Pessoa1 Oliveira, Keliane de3 Guimaraes, Fernanda Carneiro3 Barbosa, Izabela Guimaraes1 Barros, Joao Luís Vieira Monteiro de1 Okusaga, Olaoluwa2 Martins-Filho, Olindo Assis4 Salgado, Joao Vinicius1 Teixeira, Antonio Lucio1 |
| Institucions: | 1Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Minas Gerais. Brasil 2The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas. Brasil 3Fundacao Hospital Estadual de Minas Gerais, Instituto Raul Soares, Belo Horizonte, Minas Gerais. Brasil 4Fundacao Oswaldo Cruz, Centro de Pesquisas Rene Rachou, Belo Horizonte, Minas Gerais. Brasil |
| Any: | 2017 |
| Període: | Nov-Dic |
| Volum: | 44 |
| Número: | 6 |
| Paginació: | 145-148 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Toxoplasma gondii (T. gondii) infection has been identified as a risk factor for schizophrenia. Objectives: Herein, we sought to evaluate the association between T. gondii infection and clinical symptoms and quality of life in patients with schizophrenia. Methods: We conducted a cross-sectional study with 48 patients with chronic schizophrenia and 40 controls. Peripheral blood was drawn, and IgM and IgG anti-T. gondii antibodies were evaluated by Enzyme-Linked Immunosorbent Assay (ELISA). Depressive, positive and negative symptoms were assessed, respectively, by the Calgary Depression Scale (CDS) and the Positive and Negative Syndrome Scale (PANSS). Cognitive performance was assessed in patients by the Brazilian version of the Schizophrenia Cognition Rating Scale (SCoRS-BR). Quality of life was assessed by the Brazilian version of the Quality of Life in Schizophrenia scale (QLS-BR). Results: The prevalence and titers of T. gondii IgM and IgG antibodies did not differ between patients and controls. The positive serology for T. gondii IgG antibodies was not associated with illness symptoms, cognitive performance, depressive symptoms or quality of life. Discussion: Our findings suggest that toxoplasmosis infection is not associated with severity of symptoms, quality of life, cognitive or depressive symptoms in schizophrenia patients |
| Disciplines | Medicina |
| Paraules clau: | Microbiología, Psiquiatría, Toxoplasmosis, Enfermedades asociadas, Depresión, Esquizofrenia, Cognición, Calidad de vida |
| Keyword: | Medicine, Microbiology, Psychiatry, Toxoplasmosis, Associated diseases, Depression, Schizophrenia, Cognition, Quality of life |
| Text complet: | Texto completo (Ver HTML) |
