Revista: | Archives of clinical psychiatry |
Base de datos: | PERIÓDICA |
Número de sistema: | 000394247 |
Autors: | Santos, Glenda Dias1 Nunes, Paula Villela1 Stella, Florindo1 Brum, Paula Schmidt1 Yassuda, Monica Sanches2 Ueno, Linda Massako3 Gattaz, Wagner Farid1 Forlenza, Orestes Vicente1 |
Institucions: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil 2Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Biociencias, Rio Claro, Sao Paulo. Brasil 3Universidade de Sao Paulo, Escola de Artes, Ciencias e Humanidades, Sao Paulo. Brasil |
Any: | 2015 |
Període: | Nov-Dic |
Volum: | 42 |
Número: | 6 |
Paginació: | 153-156 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, caso clínico |
Resumen en inglés | Non-pharmalogical interventions represent an important complement to standard pharmalogical treatment in dementia. Objective This study aims to evaluate the effects of a multidisciplinary rehabilitation program on cognitive ability, quality of life and depression symptoms in patients with Alzheimer’s disease (AD) and cognitive impairment without dementia (CIND). Methods Ninety-seven older adults were recruited to the present study. Of these, 70 patients had mild AD and were allocated into experimental (n = 54) or control (n = 16) groups. Two additional active comparison groups were constituted with patients with moderate AD (n = 13) or with CIND (n = 14) who also received the intervention. The multidisciplinary rehabilitation program lasted for 12 weeks and was composed by sessions of memory training, recreational activities, verbal expression and writing, physical therapy and physical training, delivered in two weekly 6-hour sessions. Results As compared to controls, mild AD patients who received the intervention had improvements in cognition (p = 0.021) and quality of life (p = 0.003), along with a reduction in depressive symptoms (p < 0.001). As compared to baseline, CIND patients displayed at the end of the intervention improvements in cognition (p = 0.005) and depressive symptoms (p = 0.011). No such benefits were found among patients with moderate AD.Discussion: This multidisciplinary rehabilitation program was beneficial for patients with mild AD and CIND. However, patients with moderate dementia did not benefit from the intervention |
Disciplines | Medicina |
Paraules clau: | Neurología, Terapéutica y rehabilitación, Enfermedad de Alzheimer, Déficit cognitivo, Demencia, Tratamiento muldisciplinario |
Keyword: | Medicine, Neurology, Therapeutics and rehabilitation, Alzheimer disease, Cognitive impairment, Dementia, Multidisciplinary treatment |
Text complet: | Texto completo (Ver HTML) |