Multidisciplinary rehabilitation program: effects of a multimodal intervention for patients with Alzheimer’s disease and cognitive impairment without dementia



Título del documento: Multidisciplinary rehabilitation program: effects of a multimodal intervention for patients with Alzheimer’s disease and cognitive impairment without dementia
Revista: Archives of clinical psychiatry
Base de datos: PERIÓDICA
Número de sistema: 000394247
Autors: 1
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Institucions: 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil
2Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Biociencias, Rio Claro, Sao Paulo. Brasil
3Universidade de Sao Paulo, Escola de Artes, Ciencias e Humanidades, Sao Paulo. Brasil
Any:
Període: Nov-Dic
Volum: 42
Número: 6
Paginació: 153-156
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, caso clínico
Resumen en inglés Non-pharmalogical interventions represent an important complement to standard pharmalogical treatment in dementia. Objective This study aims to evaluate the effects of a multidisciplinary rehabilitation program on cognitive ability, quality of life and depression symptoms in patients with Alzheimer’s disease (AD) and cognitive impairment without dementia (CIND). Methods Ninety-seven older adults were recruited to the present study. Of these, 70 patients had mild AD and were allocated into experimental (n = 54) or control (n = 16) groups. Two additional active comparison groups were constituted with patients with moderate AD (n = 13) or with CIND (n = 14) who also received the intervention. The multidisciplinary rehabilitation program lasted for 12 weeks and was composed by sessions of memory training, recreational activities, verbal expression and writing, physical therapy and physical training, delivered in two weekly 6-hour sessions. Results As compared to controls, mild AD patients who received the intervention had improvements in cognition (p = 0.021) and quality of life (p = 0.003), along with a reduction in depressive symptoms (p < 0.001). As compared to baseline, CIND patients displayed at the end of the intervention improvements in cognition (p = 0.005) and depressive symptoms (p = 0.011). No such benefits were found among patients with moderate AD.Discussion: This multidisciplinary rehabilitation program was beneficial for patients with mild AD and CIND. However, patients with moderate dementia did not benefit from the intervention
Disciplines Medicina
Paraules clau: Neurología,
Terapéutica y rehabilitación,
Enfermedad de Alzheimer,
Déficit cognitivo,
Demencia,
Tratamiento muldisciplinario
Keyword: Medicine,
Neurology,
Therapeutics and rehabilitation,
Alzheimer disease,
Cognitive impairment,
Dementia,
Multidisciplinary treatment
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