Spontaneous hepatic rupture during pregnancy in a patient with peliosis hepatis



Título del documento: Spontaneous hepatic rupture during pregnancy in a patient with peliosis hepatis
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000411766
ISSN: 1665-2681
Autors: 1
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2
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Institucions: 1Ospedale Niguarda Ca’ Granda, Dipartimento Niguarda Trauma Center, Milán, Lombardia. Italia
2Ospedale Niguarda Ca’ Granda, Struttura Complessa di Anatomia Istologia Patologica e Citogenetica, Milán, Lombardia. Italia
Any:
Període: Jul-Ago
Volum: 14
Número: 4
Paginació: 553-558
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés Spontaneous hepatic rupture (SHR) during pregnancy is a rare but well known complication and it usually occurs alongside eclampsia or HELLP syndrome. SHR in uncomplicated pregnancy is extremely rare and can be associated to different undiagnosed pathological conditions. We report the case of a nulliparous woman, 27 weeks pregnant, with a peliosis hepatis, previously unknown, who was admitted to our unit due to SHR and massive hemoperitoneum. The conception was obtained by embryo transfer after multiple attempts of hormone-supported cycles using estrogens and progesterone. After emergency laparotomy the patient was submitted to deliver of the dead foetus and damage control of the hepatic bleeding source. At relaparotomy a right posterior sectionectomy (segments VI and VII) and segmentectomy of segment V were performed. The patient was discharged in good physical conditions after 18 days from admission. If hepatic rupture is suspected in a pregnant patient a collaborative multidisciplinary approach is mandatory. The cornerstones of medical and surgical management are highlighted. At the best of our knowledge this is the first case of SHR in a pregnant woman with peliosis hepatis. A possible correlation of an increased risk for SHR in a pregnant patient who was submitted to several attempts for embryo transfer is discussed. The relevant scientific literature of the possible causative role of the estrogen therapy in inducing politic liver damage is also reviewed
Disciplines Medicina
Paraules clau: Gastroenterología,
Ginecología y obstetricia,
Embarazo,
Ruptura hepática,
Hemoperitoneo,
Peliosis hepática
Keyword: Medicine,
Gastroenterology,
Gynecology and obstetrics,
Pregnancy,
Hepatic rupture,
Hemoperitoneum,
Hepatic peliosis
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