| Revista: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000419058 |
| ISSN: | 1665-2681 |
| Autors: | Taner, C. Burcin1 Bulatao, Ilynn G1 Arasi, Lisa C1 Perry, Dana K1 Willingham, Darrin L1 Sibulesky, Lena1 Rosser, Barry G1 Canabal, Juan M1 Nguyen, Justin H1 Kramer, David J1 |
| Institucions: | 1Mayo Clinic Florida, Department of Transplantation, Jacksonville, Florida. Estados Unidos de América |
| Any: | 2012 |
| Període: | Sep-Oct |
| Volum: | 11 |
| Número: | 5 |
| Paginació: | 679-685 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Patients with end stage liver disease may become critically ill prior to LT requiring admission to the intensive care unit (ICU). The high acuity patients may be thought too ill to transplant; however, often LT is the only therapeutic option. Choosing the correct liver allograft for these patients is often difficult and it is imperative that the allograft work immediately. Donation after cardiac death (DCD) donors provide an important source of livers, however, DCD graft allocation remains a controversial topic, in critically ill patients. Between January 2003-December 2008, 1215 LTs were performed: 85 patients at the time of LT were in the ICU. Twelve patients received DCD grafts and 73 received donation after brain dead (DBD) grafts. After retransplant cases and multiorgan transplants were excluded, 8 recipients of DCD grafts and 42 recipients of DBD grafts were included in this study. Post-transplant outcomes of DCD and DBD liver grafts were compared. While there were differences in graft and survival between DCD and DBD groups at 4 month and 1 year time points, the differences did not reach statistical significance. The graft and patient survival rates were similar among the groups at 3-year time point. There is need for other large liver transplant programs to report their outcomes using liver grafts from DCD and DBD donors. We believe that the experience of the surgical, medical and critical care team is important for successfully using DCD grafts for critically ill patients |
| Disciplines | Medicina |
| Paraules clau: | Gastroenterología, Cirugía, Enfermedad hepática terminal, Trasplante de hígado, Complicaciones postoperatorias, Rechazo de injerto, Sobrevivencia |
| Keyword: | Gastroenterology, Surgery, End-stage liver disease, Liver transplantation, Postoperative complications, Graft rejection, Survival |
| Text complet: | Texto completo (Ver PDF) |
