| Revista: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000411789 |
| ISSN: | 1665-2681 |
| Autors: | Faustini-Pereira, Jose L1 Homercher-Galant, Lucas1 Garcia, Eduardo1 Brandao, Ajacio Bandeira de Mello2 Marroni, Claudio A1 |
| Institucions: | 1Universidade Federal de Ciencias da Saude de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil 2Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil |
| Any: | 2015 |
| Període: | May-Jun |
| Volum: | 14 |
| Número: | 3 |
| Paginació: | 361-368 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Hepatopulmonary syndrome (HPS) is characterized by a clinical triad of liver disease and/or portal hypertension, intrapulmonary vascular dilatation and abnormal arterial oxygenation. These conditions can worsen muscle strength, exercise capacity and functionality in the affected population. Objective. The objective of this study was to compare exercise capacity, functional condition and respiratory muscle strength in cirrhotic patients diagnosed with HPS and cirrhotic patients without this diagnosis. Material and methods. This cross-sectional study used a convenience sample consisting of 178 patients (92 patients with HPS and 86 patients without HPS) with a diagnosis of liver cirrhosis caused by either alcohol consumption or the hepatitis C virus (HCV). Peak oxygen consumption (VO2 peak) was used to verify exercise capacity, the six-minute walk test (6MWT) was used to test functionality, and manovacuometry was used to evaluate the strength of the respiratory muscles. The Kolmogorov-Smirnov test and Student’s t-test were used for the statistical analysis. The data were analyzed using SPSS 16.00, and p < 0.05 was considered significant. Results. The group of patients with the diagnosis of HPS exhibited a lower VO2 peak (14.2 ± 2.3 vs. 17.6 ± 2.6, p < 0.001), shorter distance walked in the 6MWT (340.8 ± 50.9 vs. 416.5 ± 91.4, p < 0.001), lower maximal inspiratory pressure (-49.1 ± 9.8 vs. -74.2 ± 13.9, p = 0.001) and lower maximum expiratory pressure (60.1 ± 12.2 vs. 76.8 ± 14.7, p = 0.001). Conclusion. The group of cirrhotic patients diagnosed with HPS exhibited lower values for VO2 peak, distance walked in the 6MWT and respiratory muscle strength than the cirrhotic patients not diagnosed with HPS |
| Disciplines | Medicina |
| Paraules clau: | Diagnóstico, Gastroenterología, Neumología, Cirrosis hepática, Síndrome hepatopulmonar, Fuerza muscular respiratoria, Consumo máximo de oxígeno, Pruebas de ejercicio, Capacidad física |
| Keyword: | Medicine, Diagnosis, Gastroenterology, Pneumology, Liver cirrhosis, Hepatopulmonary syndrome, Respiratory muscle strength, Peak oxygen uptake, Exercise tests, Physical capacity |
| Text complet: | Texto completo (Ver PDF) |
