| Revista: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000418485 |
| ISSN: | 1665-2681 |
| Autors: | Ortiz Olvera, Nayeli X1 Castellanos Pallares, Guillermo1 Gómez Jiménez, Luz M1 Cabrera Muñoz, María L1 Méndez Navarro, Jorge1 Moran Villota, Segundo1 Dehesa Violante, Margarita1 |
| Institucions: | 1Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, México, Distrito Federal. México |
| Any: | 2011 |
| Període: | Jul-Sep |
| Volum: | 10 |
| Número: | 3 |
| Paginació: | 321-326 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | It has been suggested that liver cirrhosis (LC), regardless of etiology, may be associated with anatomical cardiac alterations. Objective. To describe the frequency and type of macroscopical anatomic cardiac abnormalities present in alcoholic and non-alcoholic cirrhotic patients in an autopsy series. Material and methods. The autopsy records performed at our institution during a 12-year period (1990-2002) were reviewed. All cases with final diagnosis of LC were included, their demographic characteristics as well as cirrhosis etiology and macroscopic anatomical cardiac abnormalities (MACA) analyzed. Patients with any known history of heart disease prior to diagnosis of cirrhosis were excluded. Results. A total of 1,176 autopsies were performed, of which 135 cases (11.5%) were patients with LC. Two patients with cardiac cirrhosis were excluded. Chronic alcohol abuse (29%) and chronic hepatitis due to hepatitis C virus (HCV) infection (20%) were the most common causes of cirrhosis. The etiology was not identified in 35% of the cases, even after exhaustive clinical, serological and/or radiological assessment. In the postmortem analysis, 43% of the cases were informed to have MACA (47% in the group of patients with alcoholic cirrhosis and 41% in other types of cirrhosis); this rate increased to 62% in patients with ascites. The most frequent alterations were cardiomegaly and left ventricular hypertrophy (LVH). Conclusion. The results confirm the high frequency of cardiac abnormalities in patients with cirrhosis, regardless of cirrhosis etiology |
| Disciplines | Medicina |
| Paraules clau: | Gastroenterología, Sistema cardiovascular, Hepatitis C, Cirrosis hepática, Alteraciones cardiovasculares, Cardiomiopatías, Hipertrofia ventricular |
| Keyword: | Gastroenterology, Cardiovascular system, Hepatitis C, Liver cirrhosis, Cardiovascular alterations, Cardiomyopathies, Ventricular hypertrophy |
| Text complet: | Texto completo (Ver PDF) |
