| Revista: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000418062 |
| ISSN: | 0001-3765 |
| Autors: | Silva, Lenise L1 Balconi, Luana S2 Gressler, Leticia T3 Garlet, Quelen I1 Sutili, Fernando J1 Vargas, Agueda P.C3 Baldisserotto, Bernardo4 Morel, Ademir F5 Heinzmann, Berta M2 |
| Institucions: | 1Universidade Federal de Santa Maria, Programa de Pos-Graduacao em Farmacologia, Santa Maria, Rio Grande do Sul. Brasil 2Universidade Federal de Santa Maria, Departamento de Farmacia Industrial, Santa Maria, Rio Grande do Sul. Brasil 3Universidade Federal de Santa Maria, Departamento de Medicina Veterinaria Preventiva, Santa Maria, Rio Grande do Sul. Brasil 4Universidade Federal de Santa Maria, Departamento de Fisiologia e Farmacologia, Santa Maria, Rio Grande do Sul. Brasil 5Universidade Federal de Santa Maria, Departamento de Quimica, Santa Maria, Rio Grande do Sul. Brasil |
| Any: | 2017 |
| Període: | Mar |
| Volum: | 89 |
| Número: | 1 |
| Paginació: | 203-212 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Linalool is the main compound of many essential oils and occurs in two isomeric forms: S-(+)- and R-(-)-linalool. This study aimed to determine if linalool isomers have different antimicrobial and anesthetic properties in fish. For this purpose, these compounds were previously isolated from Lippia alba (Mill.)N. E. Brown and Ocimum americanum L. essential oils. Antimicrobial effects were evaluated through the microdilution test against Aeromonas hydrophila, an important fish disease etiologic agent. Induction time until sedation, anesthesia and recovery time were determined in silver catfish (Rhamdia quelen) through bath exposure (60, 180, 300 or 500 μL L-1). The results showed different biological properties for the isomers being S-(+)-linalool the only active against A. hydrophila at 3.2 mg mL-1. The sedation was induced without differences between the compounds, however R-(-)-linalool promoted faster anesthesia. There were no differences regarding the recovery time of the animals exposed to the linalool isomers. Although both S-(+)- and R-(-)-linalool can be used for sedative purposes, their use in A. hydrophila infection is inadvisable due to the high effective concentration. Considering anesthesia as the main objective, the R-(-)-linalool demonstrated clear advantages at lower concentration |
| Disciplines | Biología, Medicina veterinaria y zootecnia |
| Paraules clau: | Peces, Química farmacéutica, Cultivo de peces, Manejo de peces, Anestesia, Aceites esenciales, Linalool, Actividad biológica, Aeromonas hydrophila |
| Keyword: | Fish, Medicinal chemistry, Fish culture, Fish handling, Anesthesia, Essential oils, Linalool, Biological activity, Aeromonas hydrophyla |
| Text complet: | Texto completo (Ver HTML) |
