| Revista: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000400474 |
| ISSN: | 0001-3765 |
| Autors: | Nascimento, Dayane K.D1 Souza, Ivone A. de2 Oliveira, Antonio F.M. de3 Barbosa, Mariana O3 Santana, Marllon A.N1 Pereira-Junior, Daniel F1 Lira, Eduardo C4 Vieira, Jeymesson R.C1 |
| Institucions: | 1Universidade Federal de Pernambuco, Departamento de Histologia e Embriologia, Recife, Pernambuco. Brasil 2Universidade Federal de Pernambuco, Departamento de Antibioticos, Recife, Pernambuco. Brasil 3Universidade Federal de Pernambuco, Departamento de Botanica, Recife, Pernambuco. Brasil 4Universidade Federal de Pernambuco, Departamento de Fisiologia e Farmacologia, Recife, Pernambuco. Brasil |
| Any: | 2016 |
| Període: | Sep |
| Volum: | 88 |
| Número: | 3 |
| Paginació: | 1431-1438 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Mangroves represent areas of high biological productivity and it is a region rich in bioactive substances used in medicine production. Conocarpus erectus (Combretaceae) known as button mangrove is one of the species found in mangroves and it is used in folk medicine in the treatment of anemia, catarrh, conjunctivitis, diabetes, diarrhea, fever, gonorrhea, headache, hemorrhage, orchitis, rash, bumps and syphilis. The present study aimed to investigate the acute toxicity of aqueous extract of leaves of C. erectus in Swiss albino mice. The plant material was collected in Vila Velha mangroves, located in Itamaracá (PE). The material was subjected to a phytochemical screening where extractive protocols to identify majority molecules present in leaves were used. The evaluation of acute toxicity of aqueous extract of C. erectus followed the model of Acute Toxicity Class based on OECD 423 Guideline, 2001. The majority molecules were identified: flavonoids, tannins and saponins. The LD50 was estimated at 2,000 mg/kg bw. Therefore, the aqueous extract showed low acute toxicity classified in category 5 |
| Disciplines | Biología, Química |
| Paraules clau: | Angiospermas, Fitoquímica, Plantas medicinales, Extractos vegetales, Extracto acuoso, Toxicidad aguda, Conocarpus erectus, Combretaceae |
| Keyword: | Biology, Chemistry, Angiosperms, Phytochemistry, Medicinal plants, Plant extracts, Aqueous extracts, Acute toxicity, Conocarpus erectus, Combretaceae |
| Text complet: | Texto completo (Ver HTML) |
