| Revista: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000408992 |
| ISSN: | 0001-3765 |
| Autors: | Costa, Oscar T.F. da1 Ramos, Cleverson A1 Duncan, Wallice P1 Lameiras, Juliana L.V2 Fernandes, Marisa N3 |
| Institucions: | 1Universidade Federal do Amazonas, Departamento de Morfologia, Manaus, Amazonas. Brasil 2Universidade Federal do Amazonas, Programa de Pos-Graduacao em Biotecnologia, Manaus, Amazonas. Brasil 3Universidade Federal de Sao Carlos, Departamento de Ciencias Fisiologicas, Sao Carlos, Sao Paulo. Brasil |
| Any: | 2017 |
| Període: | Jun |
| Volum: | 89 |
| Número: | 2 |
| Paginació: | 965-972 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The gill mitochondria-rich cells of the juvenile Amazonian fish Colossoma macropomum were analyzed using light and scanning and transmission electron microscopy after 96 h exposure to 0.04 and 0.2 mM nitrite. Although the number of mitochondria-rich cells decreased significantly in the lamellar epithelium, no decrease was found in the interlamellar region of the gill filament. Nitrite exposure caused significant reduction on the apical surface area of individual mitochondria-rich cells (p < 0.05), with a resulting reduction of the fractional area of these cells in both the lamellar and filament epithelium. Swelling of endoplasmic reticulum cisternae, nuclear envelope and mitochondria were the main changes found in the mitochondria-rich cells. Cristae lysis and matrix vacuolization characterized the mitochondrial changes. The overall ultrastructural changes indicated cellular functional disruption caused by exposure to nitrite. The changes observed in the gill indicate that the cellular structures involved in the process of energy production become severely damaged by exposure to nitrite indicating irreversible damage conducting to cell death |
| Disciplines | Biología |
| Paraules clau: | Fisiología animal, Peces, Ensayos de toxicidad, Nitritos, Peces de agua dulce, Agallas, Daño celular, Ultraestructura celular, Colossoma macropomum |
| Keyword: | Biology, Animal physiology, Fish, Toxicity tests, Nitrites, Freshwater fish, Gills, Cell damage, Cell structure, Colossoma macropomum |
| Text complet: | Texto completo (Ver HTML) |
