| Revista: | Anais brasileiros de dermatologia |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000408888 |
| ISSN: | 0365-0596 |
| Autors: | Bilgic, Ozlem1 |
| Institucions: | 1Selcuk University, School of Medicine, Konya. Turquía |
| Any: | 2017 |
| Període: | Mar-Abr |
| Volum: | 92 |
| Número: | 2 |
| Paginació: | 275-276 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, descriptivo |
| Resumen en inglés | Werner syndrome is a rare autosomal recessive disorder, caused by mutations in the WRN gene. Clinical findings include: senile appearance, short stature, grey hair, alopecia, bird-like face, scleroderma-like skin changes, skin ulcers, voice abnormalities, cataracts, osteoporosis, type 2 diabetes mellitus, ischemic heart disease and hypogonadism. The syndrome begins to become apparent in adolescence but it is usually diagnosed in the third or fourth decade of life. Since the patients usually die by the age of 40-50 years related to malignant neoplasms or atherosclerotic complications, they should be closely followed and treated for complications |
| Disciplines | Medicina |
| Paraules clau: | Dermatología, Diagnóstico, Ulceras dérmicas, Piernas, Progeria, Esclerodermia, Síndrome de Werner |
| Keyword: | Medicine, Dermatology, Diagnosis, Skin ulcers, Legs, Scleroderma, Werner syndrome |
| Text complet: | Texto completo (Ver HTML) |
