Discrepancies in the evaluation of the safety of the human papillomavirus vaccine



Título del documento: Discrepancies in the evaluation of the safety of the human papillomavirus vaccine
Revue: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000420031
ISSN: 0074-0276
Autores: 1
1
Instituciones: 1Texas Tech University, Health Sciences Center, El Paso, Texas. Brasil
Año:
Volumen: 113
Número: 8
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés Despite being more than ten years since its introduction, global acceptance to the human papillomavirus (HPV) vaccine is still low. The immunogenetic background of the host, and HPV antigen recognition, are important in natural HPV infection, and should be taken into account in the understanding of adverse autoimmune reactions by the HPV vaccine in certain groups. There is no doubt of the benefit of vaccines in the reduction of the incidence of infectious diseases, and in the case of HPV, the prevention of persistent infection that would lead to cervical cancer. Side-effects, however, should be closely monitored and reported without any bias, to ensure that the benefits of vaccines outweigh the risks of adverse reactions. In this article we bring the attention on certain adverse effects of the vaccine against HPV that have not been well studied as they are not well defined. We also compare the different approaches on HPV vaccine policies regarding its adverse reactions in countries like Japan and Colombia, vs. the recommendations issued by the WHO
Disciplinas: Medicina
Palabras clave: Ginecología y obstetricia,
Inmunología,
Oncología,
Virus del papiloma humano,
Vacunas,
Autoinmunidad,
Prevención de enfermedades,
Políticas de salud
Keyword: Gynecology and obstetrics,
Immunology,
Oncology,
Human papillomavirus,
Vaccines,
Autoimmunity,
Disease prevention,
Health policies
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