| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000431083 |
| ISSN: | 0034-9887 |
| Authors: | Herrera, Rodrigo1 Peñaloza, Francisco1 Arrieta, Cristóbal1 Zacconi, Flavia2 Saavedra, Víctor3 Saavedra, Carla3 Brañes, Cecilia4 Hack, Thomas1 Uribe, Sergio1 |
| Institutions: | 1Pontificia Universidad Católica de Chile, Centro de imágenes Biomédicas, Santiago de Chile. Chile 2Pontificia Universidad Católica de Chile, Facultad de Química, Santiago de Chile. Chile 3Centros de Estudios Clínicos e Investigaciones Médicas, Santiago de Chile. Chile 4Naturalis. Consorcio de Investigación, Santiago de Chile. Chile |
| Year: | 2019 |
| Season: | Jul |
| Volumen: | 147 |
| Number: | 7 |
| Pages: | 821-827 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively. Aim: To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material and Methods: Three algorithms were implemented: region growing (RG), graph cuts (GC) and hierarchical (HR), all based on the IDEAL method to obtain water and fat images. Using these images, the proton density fat fraction (PDFF) was calculated. The three methods were tested in phantoms with known fat percentages and later on we acquired images from 20 volunteers with an ultrasound diagnosis of fatty liver disease in different stages. For everyone, the PDFF of the nine liver segments was determined. Results: In phantoms, the mean error between the real fat percentage and the value obtained through the three methods was −1,26, −1 and −0,8 for RG, GC and HR, respectively. The hierarchical method was more precise and efficient to obtain PDFF. The results in volunteers revealed that ultrasound showed errors categorizing the severity of hepatic steatosis in more than 50% of volunteers. Conclusions: We developed a tool for magnetic resonance, which allows to quantify fat in the liver. This method is less operator dependent than ultrasound and describes the heterogeneity in the fat distribution along the nine hepatic segments |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Gastroenterología, Hígado graso no alcohólico, Técnicas de diagnóstico, Imagenología médica, Resonancia magnética |
| Keyword: | Diagnosis, Gastroenterology, Non alcoholic fatty liver, Diagnostic techniques, Medical imaging, Magnetic resonance |
| Full text: | Texto completo (Ver HTML) |
