Risk factors for hepatitis B transmission in South Brazil



Document title: Risk factors for hepatitis B transmission in South Brazil
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000413838
ISSN: 0074-0276
Authors: 1
1
2
2
1
3
1
1
Institutions: 1Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, Rio Grande do Sul. Brasil
2Universidade de Caxias do Sul, Caxias do Sul, Rio Grande do Sul. Brasil
3Prefeitura Municipal de Caxias do Sul, Servico Municipal de Infectologia, Caxias do Sul, Rio Grande do Sul. Brasil
Year:
Season: Ago
Volumen: 112
Number: 8
Pages: 544-550
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract Hepatitis B virus (HBV) infection is a major public health problem in Brazil. Several risk factors are involved in HBV infection and their identification by a rational and essential approach is required to prevent the transmission of this infection in Brazil. OBJECTIVES To evaluate risk factors associated with HBV infection in South Brazil. METHODS A total of 260 patients with HBV and 260 controls from Caxias do Sul (state of Rio Grande do Sul, Brazil) participated in this study. All participants were given a standard questionnaire to yield the sociodemographic information and to identify HBV risk factors. HBV infection was detected by HBsAg test in all participants. FINDINGS HBV infection in these cases was strongly associated with history of a family member HBV-infected, mainly mother [odds ratio (OR) = 4.86; 95% confidence intervals (CI): 1.69–13.91], father (OR = 5.28; 95% CI: 1.58–17.71), and/or siblings (OR = 22.16; 95% CI: 9.39–52.25); sharing personal objects (OR = 1.40; 95% CI: 1.37–2.38); and having history of blood transfusion (OR = 2.05; 95% CI: 1.10–2.84). CONCLUSIONS HBV infection was strongly associated with having a family member infected with hepatitis B, sharing personal objects, and having history of blood transfusion
Disciplines: Medicina
Keyword: Gastroenterología,
Salud pública,
Hepatitis B,
Hepatitis crónica,
Epidemiología,
Factores de riesgo,
Mecanismos de transmisión
Keyword: Medicine,
Gastroenterology,
Public health,
Hepatitis B,
Chronic hepatitis,
Epidemiology,
Risk factors,
Transmission mechanisms
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