| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000413842 |
| ISSN: | 0074-0276 |
| Authors: | Damasceno, Jeziel D1 Silva, Gabriel L.A1 Tschudi, Christian2 Tosi, Luiz R.O1 |
| Institutions: | 1Universidade de Sao Paulo, Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil 2Yale University, School of Public Health, New Haven, Connecticut. Estados Unidos de América |
| Year: | 2017 |
| Season: | Ago |
| Volumen: | 112 |
| Number: | 8 |
| Pages: | 583-585 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp. and Trypanosoma brucei and found evidences for its expression as a specific RNA class. The trypanosomatid TERRA are heterogeneous in size and partially polyadenylated. The levels of TERRA transcripts appear to be modulated through the life cycle in both trypanosomatids investigated, suggesting that TERRA play a stage-specific role in the life cycle of these early-branching eukaryotes |
| Disciplines: | Medicina |
| Keyword: | Microbiología, Genética, Protozoarios, ARN, Telómeros, Transcripción genética, Trypanosoma brucei |
| Keyword: | Medicine, Microbiology, Genetics, Protozoa, RNA, Telomeres, Genetic transcription, Trypanosoma brucei |
| Full text: | Texto completo (Ver HTML) |
