Description of an oral Chagas disease outbreak in Venezuela, including a vertically transmitted case
Document title: Description of an oral Chagas disease outbreak in Venezuela, including a vertically transmitted case
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000413841
ISSN: 0074-0276
Authors: 1
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Institutions: 1Universidad Central de Venezuela, Facultad de Medicina, Caracas, Distrito Federal. Venezuela
2Hospital de Clínicas Caracas, Departamento de Anatomía Patológica, Caracas, Distrito Federal. Venezuela
3Hospital de Clínicas Caracas, Departamento de Obstetricia y Ginecología, Caracas, Distrito Federal. Venezuela
4Clínica Sanitas Santa Paula, Caracas, Distrito Federal. Venezuela
Year:
Season: Ago
Volumen: 112
Number: 8
Pages: 580-582
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract We describe the eleventh major outbreak of foodborne Trypanosoma cruzi transmission in urban Venezuela, including evidence for vertical transmission from the index case to her fetus. After confirming fetal death at 24 weeks of gestation, pregnancy interruption was performed. On direct examination of the amniotic fluid, trypomastigotes were detected. T. cruzi specific-polymerase chain reaction (PCR) also proved positive when examining autopsied fetal organs. Finally, microscopic fetal heart examination revealed amastigote nests. Acute orally transmitted Chagas disease can be life threatening or even fatal for pregnant women and unborn fetuses owing to vertical transmission. There is therefore an urgent need to improve national epidemiologic control measures
Disciplines: Medicina
Keyword: Microbiología,
Salud pública,
Enfermedad de Chagas,
Brotes epidémicos,
Epidemiología,
Transmisión oral,
Transmisión vertical
Keyword: Medicine,
Microbiology,
Public health,
Chagas disease,
Epidemic outbreaks,
Epidemiology,
Oral transmission,
Vertical transmission
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