| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000413844 |
| ISSN: | 0074-0276 |
| Authors: | Sittivicharpinyo, Thikhumporn1 Wonnapinij, Passorn1 Surat, Wunrada1 |
| Institutions: | 1Kasetsart University, Faculty of Science, Bangkok, Phra Nakhon. Tailandia |
| Year: | 2017 |
| Season: | Ago |
| Volumen: | 112 |
| Number: | 8 |
| Pages: | 572-576 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | This report is the first to characterise the complete coding sequence of a dengue virus serotype 4 (DENV-4) genotype I that was isolated from field-caught mosquitoes from an endemic area in Thailand in June 2013. The sequence was assembled from high-throughput sequencing reads generated by Illumina HiSeq. Three out of four observed intra-sample variants caused an amino acid variation in C, NS2B, and NS5 genes. The C4279T variant located in the NS2B gene can indirectly affect the proteolytic activity of the NS3 protein. The sequence provided in this study might be useful for the epidemiological study of DENV-4 |
| Disciplines: | Medicina, Biología |
| Keyword: | Genética, Virus, Virus del dengue, Secuencia génica, Serotipos |
| Keyword: | Medicine, Biology, Genetics, Virus, Dengue virus, Gene sequence, Serotypes |
| Full text: | Texto completo (Ver HTML) |
