Chagas disease in Virgem da Lapa, Minas Gerais, Brazil: left ventricle aneurysm and the risk of death in the 24-year interval
Document title: Chagas disease in Virgem da Lapa, Minas Gerais, Brazil: left ventricle aneurysm and the risk of death in the 24-year interval
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000437122
ISSN: 0074-0276
Authors: 1
1
1
1
2
Institutions: 1Fundacao Oswaldo Cruz, Instituto Oswaldo Cruz, Rio de Janeiro. Brasil
2Fundacao Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro. Brasil
Year:
Volumen: 115
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Left ventricular aneurysm (LVA) is indicator of high morbidity in Chagas’ disease. A cross-sectional study performed identified LVA in 18.8% of the chronic chagasic patients (CCP). Determine the risk of death of patients with chronic chagasic cardiopathy (CCC) and LVA in 24-year interval. In 1995 a cohort of 298 CCP was evaluated by anamnesis, physical examination, EKG and ECHO and classified in groups: G0 = 86 without cardiopathy; G1 = 156 with cardiopathy without LVA and G2 = 56 with cardiopathy and LVA. 38 patients of G0 and G1 used benznidazole. Information about the deaths was obtained in the notary, death certificates, hospital records and family members. Were registered 113 deaths (37.9%): 107 (35.9%) attributed to cardiopathy and 6 (2.0%) to other causes (p < 0.05). Amongst these 107 deaths, 10 (11.6%) occurred in G0; 49 (31.4%) occurred in G1 and 48 (85.7%) occurred in G2 (p < 0.05). The risk of death was 2.7 and 7.4 times significantly higher in G2, than in G1 and G0, respectively. Chronic chagasic patients with LVA and ejection fraction < 45% have a higher risk of death than those without
Disciplines: Medicina
Keyword: Sistema cardiovascular,
Parasitología,
Enfermedad de Chagas,
Aneurisma ventricular izquierdo,
Mortalidad
Keyword: Cardiovascular system,
Parasitology,
Chagas disease,
Left ventricle aneurysm,
Mortality
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