Decrease in the Prevalence of Pancreatitis Associated with Primary Hyperparathyroidism: Experience at a Tertiary Referral Center
Título del documento: Decrease in the Prevalence of Pancreatitis Associated with Primary Hyperparathyroidism: Experience at a Tertiary Referral Center
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000390694
ISSN: 0034-8376
Autors: 1
2
1
2
2
1
Institucions: 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Endocrinología y Metabolismo, México, Distrito Federal. México
2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Gastroenterología, México, Distrito Federal. México
Any:
Període: May-Jun
Volum: 67
Número: 3
Paginació: 177-181
País: México
Idioma: Inglés
Tipo de documento: Estadística o encuesta
Enfoque: Analítico
Resumen en inglés Hypercalcemia is a rare but well recognized cause of acute and chronic pancreatitis. Hypercalcemia-related pancreatitis is mainly caused by primary hyperparathyroidism. The prevalence of pancreatitis in hyperparathyroidism varies worldwide and additional disease-modifying factors may play a role in its development. In 1988 the prevalence of pancreatitis secondary to primary hyperparathyroidism at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), a referral center in Mexico City, was 12.1% (95% CI: 6.7-21). Objective: To describe the current prevalence of pancreatitis secondary to primary hyperparathyroidism at the INCMNSZ. Methods: We reviewed 385 cases of primary hyperparathyroidism seen at the hospital between 1987 and 2012. Results: 26 cases with acute or chronic pancreatitis associated with primary hyperparathyroidism were documented, with a prevalence of 6.7% (95% CI: 4.6-9.7), which was lower than the 12.1% previously reported. In the present study, 20% had a history of alcohol consumption, 10% of gallstones, and 20% of ureteral calculi, compared with the previously reported 32.0, 34.6, and 40.0%, respectively. The average calcium levels were 13.1 and 13.8 mg/dl in the previous and current series, respectively. Conclusions: We found a decrease in the prevalence of pancreatitis associated with primary hyperparathyroidism from 12.1% (95% CI: 6.7-21) to 6.7% (95% CI: 4.6-9.7)
Disciplines Medicina
Paraules clau: Gastroenterología,
Salud pública,
Prevalencia,
Pancreatitis,
Hipercalcemia,
Hiperparatiroidismo,
Calcio,
Hormona paratiroidea
Keyword: Medicine,
Gastroenterology,
Public health,
Prevalence,
Pancreatitis,
Hypercalcemia,
Calcium,
Parathyroid hormone,
Hyperparathyroidism
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