Perspectives on NASH Histology: Cellular Ballooning



Título del documento: Perspectives on NASH Histology: Cellular Ballooning
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000409304
ISSN: 1665-2681
Autors: 1
2
Institucions: 1The University of Virginia, Division of GI/Hepatology, Charlottesville, Virginia. Estados Unidos de América
2The University of Graz, Department of Pathology, Graz, Estiria. Austria
Any:
Període: Mar-Abr
Volum: 16
Número: 2
Paginació: 182-184
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico
Resumen en inglés Interpretation of liver biopsy in NAFLD can be challenging to distinguish histological NASH from non-NASH fatty liver – a broad dichotomy which carries significant prognostic and therapeutic implications and underlies the utility of many non-invasive tests. There is usually a reasonable degree of inter-observer agreement for some key parameters like steatosis, inflammation and fibrosis staging. However, the assessment of cellular ballooning can be a stumbling block even for experienced observers. Below, we recount some aspects of the history of histological definitions in NASH and propose specific methods to more objectively identify cellular ballooning in routine biopsy assessments
Disciplines Medicina
Paraules clau: Gastroenterología,
Biología celular,
Biopsia,
Hígado,
Histología,
Esteatohepatitis no alcohólica,
Hígado graso no alcohólico,
Interpretación,
Hepatocitos
Keyword: Medicine,
Gastroenterology,
Cell biology,
Biopsy,
Liver,
Histology,
Non-alcoholic steatohepatitis,
Non alcoholic fatty liver,
Interpretation,
Hepatocytes
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