Prognostic Value of Dobutamine Stress Echocardiography in Predicting Major Cardiac Events in Patients with Metabolic Syndrome



Document title: Prognostic Value of Dobutamine Stress Echocardiography in Predicting Major Cardiac Events in Patients with Metabolic Syndrome
Journal: Revista de investigación clínica
Database: PERIÓDICA
System number: 000390714
ISSN: 0034-8376
Authors: 1
2
2
2
2
2
Institutions: 1Instituto Mexicano del Seguro Social, Hospital General de Zona 21, León, Guanajuato. México
2Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad 1, León, Guanajuato. México
Year:
Season: May-Jun
Volumen: 67
Number: 3
Pages: 199-206
Country: México
Language: Inglés
Document type: Estadística o encuesta
Approach: Analítico
English abstract The metabolic syndrome increases cardiovascular mortality. We report the mid-term prognostic value of dobutamine echocardiography for metabolic syndrome. Patients and methods: A dobutamine echocardiography protocol was performed in patients aged 18 years of age or older who suffered from chest pain and who were followed-up for two years. The patients were divided in two groups, with and without metabolic syndrome. Statistical analyses were performed using ROC curves and survival analysis; the Begg-Greenes method was used to correct for verification bias. We included 128 patients, 66 with metabolic syndrome and 62 without. Results: Forty-one patients with metabolic syndrome and 36 without had positive dobutamine echocardiography test results (p = 0.77). Coronary artery disease was found in 27 patients with metabolic syndrome and in 29 without metabolic syndrome; percutaneous revascularization was required in 24 and 26 patients, respectively (p = 0.29). Cardiovascular events occurred in 28 patients during follow-up (19 in metabolic syndrome vs. 9 in non-metabolic syndrome; p = 0.17). The odds ratio of major cardiovascular events in the metabolic syndrome group was 5.8 (95% CI: 1.74-19.60); in the control group it was 8.6 (95% CI: 2.53-29.59). Conclusion: Dobutamine echocardiography for metabolic syndrome has high sensitivity but is not a determining factor for mid-term prognosis
Disciplines: Medicina
Keyword: Diagnóstico,
Metabolismo y nutrición,
Sistema cardiovascular,
Síndrome metabólico,
Ecocardiografía,
Dobutamina,
Enfermedad coronaria,
Pruebas diagnósticas,
Valor pronóstico
Keyword: Medicine,
Cardiovascular system,
Diagnosis,
Metabolism and nutrition,
Metabolic syndrome,
Echocardiography,
Dobutamine,
Coronary artery disease,
Diagnostic tests,
Prognostic factors
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