| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000313416 |
| ISSN: | 0100-4042 |
| Authors: | Vila, Marta Maria Duarte Carvalho1 Oliveira, Robson Machado de Goncalves, Marcos Moises Tubino, Matthieu2 |
| Institutions: | 1Universidade de Sorocaba, Sorocaba, Sao Paulo. Brasil 2Universidade Estadual de Campinas, Instituto de Quimica, Campinas, Sao Paulo. Brasil |
| Year: | 2007 |
| Season: | Abr |
| Volumen: | 30 |
| Number: | 2 |
| Pages: | 395-399 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Vancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Antibióticos, Fluidos biológicos, Vancomicina, Análisis cuantitativo |
| Keyword: | Chemistry, Medicinal chemistry, Antibiotics, Biological fluids, Vancomycin, Quantitative analysis |
| Full text: | Texto completo (Ver HTML) |
