Molecular detection of mixed infections with multiple dengue virus serotypes in suspected dengue samples in Tamaulipas, Mexico



Document title: Molecular detection of mixed infections with multiple dengue virus serotypes in suspected dengue samples in Tamaulipas, Mexico
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000405576
ISSN: 0074-0276
Authors: 1
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Institutions: 1Instituto Politécnico Nacional, Centro de Biotecnología Genómica, Reynosa, Tamaulipas. México
Year:
Season: Jul
Volumen: 112
Number: 7
Pages: 520-522
Country: Brasil
Language: Inglés
Document type: Correspondencia
Approach: Experimental, aplicado
English abstract This study aimed to detect dengue virus (DENV) serotypes in serum samples obtained in Matamoros Tamaulipas, Mexico, and to determine the concordance of conventional nested reverse transcriptase polymerase chain reaction (RT-PCR) and a serological test [enzyme-linked immunosorbent assay (ELISA NS1)]. Here, we detected mixed infections consisting of four serotypes of DENV. The most prevalent serotype was DENV-1, followed by DENV-4. This is the first report of DENV-4 in our region. Mixed infections were also detected in 21.5% of samples, and the predominant coinfection consisted of DENV-1 and DENV-2. Therefore, continuous epidemiological surveillance of DENV in this area is required to predict future forms of dengue heterologous infections and the effect of this on health care
Disciplines: Medicina
Keyword: Diagnóstico,
Virus,
Flavivirus,
Virus del dengue,
Serotipificación
Keyword: Medicine,
Diagnosis,
Virus,
Flavivirus,
Dengue virus,
Serotyping
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