Evaluation of shrinkage temperature of bovine pericardium tissue for bioprosthetic heart valve application by differential scanning calorimetry and freeze-drying microscopy



Document title: Evaluation of shrinkage temperature of bovine pericardium tissue for bioprosthetic heart valve application by differential scanning calorimetry and freeze-drying microscopy
Journal: Materials research
Database: PERIÓDICA
System number: 000312974
ISSN: 1516-1439
Authors: 1


2
Institutions: 1Universidade de Sao Paulo, Escola de Ciencias Farmaceuticas, Sao Paulo. Brasil
2Universidade de Sao Paulo, Instituto de Quimica, Sao Paulo. Brasil
Year:
Season: Ene-Mar
Volumen: 10
Number: 1
Pages: 1-4
Country: Brasil
Language: Inglés
Document type: Nota breve o noticia
Approach: Experimental
English abstract Bovine pericardium bioprosthesis has become a commonly accepted device for heart valve replacement. Present practice relies on the measurement of shrinkage temperature, observed as a dramatic shortening of tissue length. Several reports in the last decade have utilized differential scanning calorimetry (DSC) as an alternative method to determine the shrinkage temperature, which is accompanied by the absorption of heat, giving rise to an endothermic peak over the shrinkage temperature range of biological tissues. Usually, freeze-drying microscope is used to determine collapse temperature during the lyophilization of solutions. On this experiment we used this technique to study the shrinkage event. The aim of this work was to compare the results of shrinkage temperature obtained by DSC with the results obtained by freeze-drying microscopy. The results showed that both techniques provided excellent sensitivity and reproducibility, and gave information on the thermal shrinkage transition via the thermodynamical parameters inherent of each method
Disciplines: Ingeniería,
Medicina veterinaria y zootecnia
Keyword: Ingeniería de materiales,
Medicina veterinaria,
Pericardio bovino,
Biomateriales,
Temperatura,
Calorimetría diferencial de barrido
Keyword: Engineering,
Veterinary medicine and animal husbandry,
Materials engineering,
Veterinary medicine,
Bovine pericardium,
Biomaterials,
Temperature,
Differential scanning calorimetry
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