Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial



Document title: Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
Journal: Materials research
Database: PERIÓDICA
System number: 000312961
ISSN: 1516-1439
Authors: 1


2
3
Institutions: 1Universidad de La Habana, La Habana. Cuba
2Ministerio de la Industria Básica, La Habana. Cuba
3Universidad de Barcelona, Facultad de Geología, Barcelona. España
Year:
Season: Ene-Mar
Volumen: 10
Number: 1
Pages: 15-20
Country: Brasil
Language: Inglés
Document type: Nota breve o noticia
Approach: Experimental
English abstract The effect of the method of sterilization on the physical, chemical and mechanical properties of a new bone repairing material was studied. The material was obtained by thermal hydrolysis of b-tricalcium phosphate/orthophosphoric acid cement and was composed of calcium deficient hydroxyapatite, octacalcium phosphate (OCP), and b-tricalcium phosphate. Partial decomposition of the OCP was observed after sterilization for the three methods. Decomposition increased to the following sequence of sterilization methods: ethylene oxide; autoclaving; dry oven. On the other hand, mechanical strength decreased with regard to non sterilized material in the sterilization sequence: ethylene oxide; dry oven; autoclaving. The compressive strength was 8.5 ± 1.0; 9.0 ± 1.2; 8.2 ± 0.8 and 6.5 ± 1.0 MPa, whereas diametral tensile strength was 2.1 ± 0.3; 2.5 ± 0.1; 1.9 ± 0.9 and 1.6 ± 0.3 for the material sterilized by ethylene oxide, dry oven, and autoclaving, respectively. Several compositional and microstuctural changes were detected after dry heat and autoclave sterilization. Ethylene oxide sterilization had lesser effect on the chemical composition and strength than dry heat and autoclaving
Disciplines: Ingeniería,
Medicina,
Química
Keyword: Ingeniería de materiales,
Traumatología y ortopedia,
Bioquímica,
Injertos,
Biomateriales,
Fosfato tricálcico,
Esterilización,
Propiedades fisicoquímicas,
Propiedades mecánicas
Keyword: Engineering,
Medicine,
Chemistry,
Materials engineering,
Traumatology and orthopedics,
Biochemistry,
Grafts,
Biomaterials,
Tricalcium phosphate,
Sterilization,
Physicochemical properties,
Mechanical properties
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