Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds



Document title: Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
Journal: Materials research
Database: PERIÓDICA
System number: 000312970
ISSN: 1516-1439
Authors: 1


2
Institutions: 1Universidade Federal de Minas Gerais, Departamento de Engenharia Metalurgica e de Materiais, Belo Horizonte, Minas Gerais. Brasil
2Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Belo Horizonte, Minas Gerais. Brasil
Year:
Season: Ene-Mar
Volumen: 10
Number: 1
Pages: 27-29
Country: Brasil
Language: Inglés
Document type: Nota breve o noticia
Approach: Experimental
English abstract Bone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al2O3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR
Disciplines: Ingeniería,
Medicina
Keyword: Ingeniería de materiales,
Traumatología y ortopedia,
Regeneración ósea,
Alúmina,
Zinc,
Biomateriales,
Biocerámica,
Propiedades mecánicas,
Biocompatibilidad
Keyword: Engineering,
Medicine,
Materials engineering,
Traumatology and orthopedics,
Bone regeneration,
Alumina,
Zinc,
Biomaterials,
Bioceramics,
Mechanical properties,
Biocompatibility
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