Cerebral hemodynamic and metabolic changes in fulminant hepatic failure



Document title: Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000407945
ISSN: 0004-282X
Authors: 1
1
1
1
1
1
1
Institutions: 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil
Year:
Season: Jul
Volumen: 75
Number: 7
Pages: 470-476
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF
Portuguese abstract O edema cerebral e a hipertensão intracraniana (HIC) são as principais causas de morbidade e mortalidade de pacientes com insuficiência hepática fulminante (IHF). A patogênese dessas complicações tem sido investigada no homem, em modelos experimentais e em sistemas celulares isolados. Atualmente, o mecanismo subjacente ao edema cerebral e HIC na presença de IHF é multifatorial em etiologia e pouco compreendido na literatura. O objetivo deste trabalho é revisar a fisiopatologia das alterações hemodinâmicas e metabólicas cerebrais na IHF, visando melhorar a compreensão da complicação da hemodinâmica encefálica na IHF
Disciplines: Medicina
Keyword: Gastroenterología,
Neurología,
Sistema cardiovascular,
Insuficiencia hepática fulminante,
Edema cerebral,
Hipertensión intracraneana,
Fisiopatología
Keyword: Medicine,
Cardiovascular system,
Gastroenterology,
Neurology,
Fulminant hepatic failure,
Brain edema,
Intracranial hypertension,
Physiopathology
Full text: Texto completo (Ver HTML)