Association between periodontal disease and acute coronary syndrome



Document title: Association between periodontal disease and acute coronary syndrome
Journal: Arquivos brasileiros de cardiologia
Database: PERIÓDICA
System number: 000289124
ISSN: 0066-782X
Authors: 1
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Institutions: 1Pontificia Universidade Catolica do Rio Grande do Sul, Hospital Sao Lucas, Porto Alegre, Rio Grande do Sul. Brasil
Year:
Season: Feb
Volumen: 88
Number: 2
Pages: 185-190
Country: Brasil
Language: Portugués, inglés
Document type: Estadística o encuesta
Approach: Analítico
English abstract OBJECTIVE: To evaluate the relationship between PD and ACS and the association of PD and periodontitis in ACS patients. METHODS: Fifty-eight ACS patients and 57 controls with no history of coronary artery disease (CAD) were included in the study. Variables: arterial hypertension, diabetes, dyslipidemia, obesity, history of CAD, cigarette smoking, and interleukin-1beta gene polymorphism. RESULTS: One hundred and fifteen subjects were enrolled in the study. In the ACS group, 58 patients were evaluated, 32 of whom (55.2%) were male and 26 (44.8%), female. In the control group, 57 subjects were evaluated, 32 (56.1%) of whom were male and 25 (43.9%), female. Periodontal disease was diagnosed in 26 (44.8%) ACS patients and 15 (26.6%) control patients (beta2 = 4.43, p = 0.04). In a logistic regression analysis, the odds ratio for association between PD and ACS was 1.8 (95% CI: 1.0-5.0); p = 0.24. The odds ratio for association of periodontitis with ACS was 4.5 (95% CI: 1.3-15.6); p = 0.019. CONCLUSION: No independent association was found between PD and ACS. There was an independent association between periodontitis and ACS
Portuguese abstract OBJETIVO: Analisar a relação entre a DP e SCA e verificar a associação entre a DP e periodontite em pacientes com SCA. MÉTODOS: Foram incluídos 58 pacientes com diagnóstico de SCA e 57 controles, sem história de doença arterial coronariana (DAC). Variáveis: hipertensão arterial, diabete, dislipidemia, obesidade, história de DAC, tabagismo e polimorfismo genético do gene da interleucina-1beta. RESULTADOS: Fizeram parte do estudo 115 indivíduos. No grupo SCA, 58 pacientes foram avaliados, sendo 32 (55,2%) do sexo masculino e 26 (44,8%) do sexo feminino. No grupo controle, 57 indivíduos, sendo 32 (56,1%) do sexo masculino e 25 (43,9%) do sexo feminino. Verificou-se DP em 26 (44,8%) pacientes com SCA e em 15 (26,6%) pacientes do grupo controle (beta2 = 4,43, p = 0,04). Análise pela regressão logística, para a associação entre DP e SCA, demonstrou RC de 1,8 (IC 95%: 1,0-5,0); p = 0,24. A associação de periodontite com SCA apresentou RC: 4,5 (IC 95%: 1,3-15,6); p = 0,019. CONCLUSÃO: Não observamos associação independente entre a DP e SCA. Houve associação independente entre periodontite e SCA
Disciplines: Medicina
Keyword: Odontología,
Sistema cardiovascular,
Enfermedad periodontal,
Periodontitis,
Enfermedad coronaria
Keyword: Medicine,
Cardiovascular system,
Dentistry,
Periodontal disease,
Periodontitis,
Coronary artery disease
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