Journal: | Annals of hepatology |
Database: | PERIÓDICA |
System number: | 000406068 |
ISSN: | 1665-2681 |
Authors: | Putra, Juan1 Anderson, Todd A2 Roayaie, Sasan2 Maeda, Miho3 Thung, Swan N1 |
Institutions: | 1Icahn School of Medicine at Mount Sinai, Department of Pathology, Nueva York. Estados Unidos de América 2Lenox Hill Hospital, Department of Surgery, Houston, Texas. Estados Unidos de América 3Icahn School of Medicine at Mount Sinai, Department of Medicine, Nueva York. Estados Unidos de América |
Year: | 2017 |
Season: | Ene-Feb |
Volumen: | 16 |
Number: | 1 |
Pages: | 157-159 |
Country: | México |
Language: | Inglés |
Document type: | Artículo |
Approach: | Caso clínico, analítico |
English abstract | Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is a rare primary hepatic neoplasm with female predominance and relatively good prognosis. We report a 73-year-old female with chronic hepatitis B who developed metastatic lesions 5 years after underwent resection for LEL-HCC. The metastatic lesions showed a spectrum of morphologic findings, which could be mistaken for other entities such as lymphoma, particularly in lesions with single-cell infiltrative pattern and abundant tumor-infiltrating lymphocytes. Immunohistochemical study to confirm the origin of the neoplastic cells is important to make the diagnosis. We also highlighted the clinicopathologic correlation and potential therapeutic implication of programmed death ligand-1 expression in LEL-HCC |
Disciplines: | Medicina |
Keyword: | Diagnóstico, Gastroenterología, Oncología, Linfoepitelioma, Carcinoma hepatocelular, Hepatitis B, Hepatitis crónica, Metástasis, PD-1, Histología |
Keyword: | Medicine, Diagnosis, Gastroenterology, Oncology, Lymphoepithelioma, Hepatocellular carcinoma, Hepatitis B, Chronic hepatitis, Metastasis, PD-1, Histology |
Full text: | Texto completo (Ver HTML) |