| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000409344 |
| ISSN: | 1665-2681 |
| Authors: | Ip, Stephen1 Hussaini, Trana2 Daulat, Aliya2 Nalufar, Partovi2 Erb, Siegfried R1 Yoshida, Eric M1 Márquez, Vladimir1 |
| Institutions: | 1University of British Columbia, Department of Medicine, Vancouver, Columbia Británica. Canadá 2University of British Columbia, Faculty of Pharmaceutical Sciences, Vancouver, Columbia Británica. Canadá |
| Year: | 2017 |
| Season: | Mar-Abr |
| Volumen: | 16 |
| Number: | 2 |
| Pages: | 230-235 |
| Country: | México |
| Language: | Inglés |
| Document type: | Estadística o encuesta |
| Approach: | Analítico |
| English abstract | Chronic renal failure (CRF) is a significant cause of morbidity and mortality in post-liver transplantation (LT) recipients. The risk factors associated with the development of renal dysfunction are not clearly elucidated. Objectives. To examine the risk factors in the development of CRF in these patients. Material and methods. Material and methods. Retrospective case-cohort of liver transplant patients without baseline kidney dysfunction who developed chronic renal failure during their follow-up. Results. Of 370 patients, 254 met the inclusion criteria. 30% (76) of these patients had CRF of which 57% (43) were male. Age, estimated glomerular filtration rate (eGFR) at discharge, and HCV infection were found to be risk factors for CRF post-LT. The odds ratio of developing CRF was 1.4 (0.6-3.3) in males with HCV, 1.6 (0.7-3.9) in females without HCV and 4.4 (1.5-13.2) among females with HCV when compared to men without HCV. Conclusions. In this cohort of LT receipients of a major Canadian city, age, eGFR, and HCV infection were risk factors for CRF. Female gender and HCV increased this odds by a factor of more than 4 |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Nefrología, Hígado, Trasplantes, Insuficiencia hepática, Calcineurina, Inhibidores, Género, Pronóstico, Factores de riesgo |
| Keyword: | Medicine, Gastroenterology, Nephrology, Liver, Transplantation, Renal failure, Calcineurin, Inhibitors, Gender, Prognosis, Risk factors |
| Full text: | Texto completo (Ver PDF) |
