| Journal: | Anais brasileiros de dermatologia |
| Database: | PERIÓDICA |
| System number: | 000404084 |
| ISSN: | 0365-0596 |
| Authors: | Avancini, Joao1 Sanches, Jose Antonio1 Cherubim, Andre Pires Zanata1 Pazzini, Renato1 Oliveira, Cristina Mendes de1 Sumita, Laura Masami1 Valente, Neusa Yuriko Sakai1 Pannuti, Claudio Sergio1 Festa-Neto, Cyro1 |
| Institutions: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
| Year: | 2016 |
| Season: | Nov-Dic |
| Volumen: | 91 |
| Number: | 6 |
| Pages: | 738-742 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma |
| Disciplines: | Medicina |
| Keyword: | Dermatología, Oncología, Virus, Herpesvirus humano-8, VIH, Hemangiosarcoma, Células endoteliales, Sarcoma de Kaposi, Patogénesis |
| Keyword: | Medicine, Dermatology, Oncology, Virus, Human herpesvirus-8, HIV, Hemangiosarcoma, Endothelial cells, Kaposi sarcoma, Pathogenesis |
| Full text: | Texto completo (Ver HTML) |
